PERSPECTIVE:

Mike West, Geoffrey S. Ginsburg, Andrew T. Huang, and Joseph R. Nevins

Embracing the complexity of genomic data for personalized medicine
Genome Res. 2006 16: 559-566. [Abstract] [Full Text] [PDF]  

ARTICLES:

Mizuki Ohno, Tomofumi Miura, Masato Furuichi, Yohei Tominaga, Daisuke Tsuchimoto, Kunihiko Sakumi, and Yusaku Nakabeppu

A genome-wide distribution of 8-oxoguanine correlates with the preferred regions for recombination and single nucleotide polymorphism in the human genome
Genome Res. 2006 16: 567-575. [Abstract] [Full Text] [PDF] [Supplemental Research Data]  

LETTERS:

Xinwei She, Ge Liu, Mario Ventura, Shaying Zhao, Doriana Misceo, Roberta Roberto, Maria Francesca Cardone, Mariano Rocchi, NISC Comparative Sequencing Program, Eric D. Green, Nicoletta Archidiacano, and Evan E. Eichler

A preliminary comparative analysis of primate segmental duplications shows elevated substitution rates and a great-ape expansion of intrachromosomal duplications
Genome Res. 2006 16: 576-583. Published in Advance April 10, 2006, 10.1101/gr.4949406 [Abstract] [Full Text] [PDF] [Supplemental Research Data]  

Aaron T. Hamilton, Stuart Huntley, Mary Tran-Gyamfi, Daniel M. Baggott, Laurie Gordon, and Lisa Stubbs

Evolutionary expansion and divergence in the ZNF91 subfamily of primate-specific zinc finger genes
Genome Res. 2006 16: 584-594. Published in Advance April 10, 2006, 10.1101/gr.4843906 [Abstract] [Full Text] [PDF] [Supplemental Research Data]  

Mark Bieda, Xiaoqin Xu, Michael A. Singer, Roland Green, and Peggy J. Farnham

Unbiased location analysis of E2F1-binding sites suggests a widespread role for E2F1 in the human genome
Genome Res. 2006 16: 595-605. Published in Advance April 10, 2006, 10.1101/gr.4887606 [Abstract] [Full Text] [PDF] [Supplemental Research Data]  

Nansheng Chen and Lincoln D. Stein

Conservation and functional significance of gene topology in the genome of Caenorhabditis elegans
Genome Res. 2006 16: 606-617. Published in Advance April 10, 2006, 10.1101/gr.4515306 [Abstract] [Full Text] [PDF] [Supplemental Research Data] OPEN ACCESS ARTICLE  

Guangming He, Xiaojin Luo, Feng Tian, Kegui Li, Zuofeng Zhu, Wei Su, Xiaoyin Qian, Yongcai Fu, Xiangkun Wang, Chuanqing Sun, and Jinshui Yang

Haplotype variation in structure and expression of a gene cluster associated with a quantitative trait locus for improved yield in rice
Genome Res. 2006 16: 618-626. Published in Advance April 10, 2006, 10.1101/gr.4814006 [Abstract] [Full Text] [PDF] [Supplemental Research Data]  

Markus J. Herrgård, Baek-Seok Lee, Vasiliy Portnoy, and Bernhard Ø. Palsson

Integrated analysis of regulatory and metabolic networks reveals novel regulatory mechanisms in Saccharomyces cerevisiae
Genome Res. 2006 16: 627-635. Published in Advance April 10, 2006, 10.1101/gr.4083206 [Abstract] [Full Text] [PDF] [Supplemental Research Data]  

Weilong Hao and G. Brian Golding

The fate of laterally transferred genes: Life in the fast lane to adaptation or death
Genome Res. 2006 16: 636-643. [Abstract] [Full Text] [PDF] OPEN ACCESS ARTICLE  

Pooja Rawal, Veera Bhadra Rao Kummarasetti, Jinoy Ravindran, Nirmal Kumar, Kangkan Halder, Rakesh Sharma, Mitali Mukerji, Swapan Kumar Das, and Shantanu Chowdhury

Genome-wide prediction of G4 DNA as regulatory motifs: Role in Escherichia coli global regulation
Genome Res. 2006 16: 644-655. [Abstract] [Full Text] [PDF] [Supplemental Research Data]  

METHODS:

Mathieu Blanchette, Alain R. Bataille, Xiaoyu Chen, Christian Poitras, Josée Laganière, Céline Lefèbvre, Geneviève Deblois, Vincent Giguère, Vincent Ferretti, Dominique Bergeron, Benoit Coulombe, and François Robert

Genome-wide computational prediction of transcriptional regulatory modules reveals new insights into human gene expression
Genome Res. 2006 16: 656-668. Published in Advance April 10, 2006, 10.1101/gr.4866006 [Abstract] [Full Text] [PDF] [Supplemental Research Data]  

RESOURCES:

Stuart Huntley, Daniel M. Baggott, Aaron T. Hamilton, Mary Tran-Gyamfi, Shan Yang, Joomyeong Kim, Laurie Gordon, Elbert Branscomb, and Lisa Stubbs

A comprehensive catalog of human KRAB-associated zinc finger genes: Insights into the evolutionary history of a large family of transcriptional repressors
Genome Res. 2006 16: 669-677. Published in Advance April 10, 2006, 10.1101/gr.4842106 [Abstract] [Full Text] [PDF] [Supplemental Research Data]  

Marijke J. van Baren and Michael R. Brent

Iterative gene prediction and pseudogene removal improves genome annotation
Genome Res. 2006 16: 678-685. [Abstract] [Full Text] [PDF] [Supplemental Research Data] OPEN ACCESS ARTICLE  

Mohammad Arifuzzaman, Maki Maeda, Aya Itoh, Kensaku Nishikata, Chiharu Takita, Rintaro Saito, Takeshi Ara, Kenji Nakahigashi, Hsuan-Cheng Huang, Aki Hirai, Kohei Tsuzuki, Seira Nakamura, Mohammad Altaf-Ul-Amin, Taku Oshima, Tomoya Baba, Natsuko Yamamoto, Tomoyo Kawamura, Tomoko Ioka-Nakamichi, Masanari Kitagawa, Masaru Tomita, Shigehiko Kanaya, Chieko Wada, and Hirotada Mori

Large-scale identification of protein–protein interaction of Escherichia coli K-12
Genome Res. 2006 16: 686-691. Published in Advance April 10, 2006, 10.1101/gr.4527806 [Abstract] [Full Text] [PDF] [Supplemental Research Data]  

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