ARTICLES:

Gregory M. Cooper, Eric A. Stone, George Asimenos, NISC Comparative Sequencing Program, Eric D. Green, Serafim Batzoglou, and Arend Sidow

Distribution and intensity of constraint in mammalian genomic sequence
Genome Res. 2005 15: 901-913. Published in Advance June 17, 2005, 10.1101/gr.3577405 [Abstract] [Full Text] [PDF] [Supplemental Research Data]  

LETTERS:

Julie E. Horvath, Cassandra L. Gulden, Rhea U. Vallente, Marla Y. Eichler, Mario Ventura, John D. McPherson, Tina A. Graves, Richard K. Wilson, Stuart Schwartz, Mariano Rocchi, and Evan E. Eichler

Punctuated duplication seeding events during the evolution of human chromosome 2p11
Genome Res. 2005 15: 914-927. Published in Advance June 17, 2005, 10.1101/gr.3916405 [Abstract] [Full Text] [PDF] [Supplemental Research Data]  

Gabriela G. Loots, Michaela Kneissel, Hansjoerg Keller, Myma Baptist, Jessie Chang, Nicole M. Collette, Dmitriy Ovcharenko, Ingrid Plajzer-Frick, and Edward M. Rubin

Genomic deletion of a long-range bone enhancer misregulates sclerostin in Van Buchem disease
Genome Res. 2005 15: 928-935. Published in Advance June 17, 2005, 10.1101/gr.3437105 [Abstract] [Full Text] [PDF] [Supplemental Research Data] OPEN ACCESS ARTICLE  

Miri Cohen-Zinder, Eyal Seroussi, Denis M. Larkin, Juan J. Loor, Annelie Everts-van der Wind, Jun-Heon Lee, James K. Drackley, Mark R. Band, A.G. Hernandez, Moshe Shani, Harris A. Lewin, Joel I. Weller, and Micha Ron

Identification of a missense mutation in the bovine ABCG2 gene with a major effect on the QTL on chromosome 6 affecting milk yield and composition in Holstein cattle
Genome Res. 2005 15: 936-944. [Abstract] [Full Text] [PDF] [Supplemental Research Data]  

Long J. Lu, Yu Xia, Alberto Paccanaro, Haiyuan Yu, and Mark Gerstein

Assessing the limits of genomic data integration for predicting protein networks
Genome Res. 2005 15: 945-953. [Abstract] [Full Text] [PDF]  

Victor Kunin, Leon Goldovsky, Nikos Darzentas, and Christos A. Ouzounis

The net of life: Reconstructing the microbial phylogenetic network
Genome Res. 2005 15: 954-959. Published in Advance June 17, 2005, 10.1101/gr.3666505 [Abstract] [Full Text] [PDF] [Supplemental Research Data]  

METHODS:

Adele A. Mitchell, Aravinda Chakravarti, and David J. Cutler

On the probability that a novel variant is a disease-causing mutation
Genome Res. 2005 15: 960-966. Published in Advance June 17, 2005, 10.1101/gr.3761405 [Abstract] [Full Text] [PDF] [Supplemental Research Data]  

Khalid K. Alharbi, Mohammed A. Aldahmesh, Emmanuel Spanakis, Lema Haddad, Roslyn A. Whittall, Xiao-he Chen, Hamid Rassoulian, Matt J. Smith, Julie Sillibourne, Nicola J. Ball, Nikki J. Graham, Patricia J. Briggs, Iain A. Simpson, David I.W. Phillips, Deborah A. Lawlor, Shu Ye, Stephen E. Humphries, Cyrus Cooper, George Davey Smith, Shah Ebrahim, Diana M. Eccles, and Ian N.M. Day

Mutation scanning by meltMADGE: Validations using BRCA1 and LDLR, and demonstration of the potential to identify severe, moderate, silent, rare, and paucimorphic mutations in the general population
Genome Res. 2005 15: 967-977. [Abstract] [Full Text] [PDF] [Supplemental Research Data]  

Eric A. Stone and Arend Sidow

Physicochemical constraint violation by missense substitutions mediates impairment of protein function and disease severity
Genome Res. 2005 15: 978-986. Published in Advance June 17, 2005, 10.1101/gr.3804205 [Abstract] [Full Text] [PDF] [Supplemental Research Data]  

Philipp Kapranov, Jorg Drenkow, Jill Cheng, Jeffrey Long, Gregg Helt, Sujit Dike, and Thomas R. Gingeras

Examples of the complex architecture of the human transcriptome revealed by RACE and high-density tiling arrays
Genome Res. 2005 15: 987-997. [Abstract] [Full Text] [PDF] [Supplemental Research Data]  

Ali Bashir, Chun Ye, Alkes L. Price, and Vineet Bafna

Orthologous repeats and mammalian phylogenetic inference
Genome Res. 2005 15: 998-1006. [Abstract] [Full Text] [PDF] [Supplemental Research Data]  

RESOURCES:

C. Victor Jongeneel, Mauro Delorenzi, Christian Iseli, Daixing Zhou, Christian D. Haudenschild, Irina Khrebtukova, Dmitry Kuznetsov, Brian J. Stevenson, Robert L. Strausberg, Andrew J.G. Simpson, and Thomas J. Vasicek

An atlas of human gene expression from massively parallel signature sequencing (MPSS)
Genome Res. 2005 15: 1007-1014. [Abstract] [Full Text] [PDF] [Supplemental Research Data]  

Eric J. Alm, Katherine H. Huang, Morgan N. Price, Richard P. Koche, Keith Keller, Inna L. Dubchak, and Adam P. Arkin

The MicrobesOnline Web site for comparative genomics
Genome Res. 2005 15: 1015-1022. [Abstract] [Full Text] [PDF] OPEN ACCESS ARTICLE  

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