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Volume 14, Issue 1: January 2004 [Index by Author]  [Cover Caption]  Supplemental Research Data

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  ARTICLES
  LETTERS
  METHODS
  RESOURCES
  ERRATA
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ARTICLES:

Angel Amores, Tohru Suzuki, Yi-Lin Yan, Jordan Pomeroy, Amy Singer, Chris Amemiya, and John H. Postlethwait
Developmental Roles of Pufferfish Hox Clusters and Genome Evolution in Ray-Fin Fish
Genome Res. 2004 14: 1-10. [Abstract] [Full Text] [Supplemental Research Data]  

LETTERS:

Chi-hua Chiu, Ken Dewar, Günter P. Wagner, Kazuhiko Takahashi, Frank Ruddle, Christina Ledje, Peter Bartsch, Jean-Luc Scemama, Edmund Stellwag, Claudia Fried, Sonja J. Prohaska, Peter F. Stadler, and Chris T. Amemiya
Bichir HoxA Cluster Sequence Reveals Surprising Trends in Ray-Finned Fish Genomic Evolution
Genome Res. 2004 14: 11-17. [Abstract] [Full Text] [Supplemental Research Data]  

Harold Riethman, Anthony Ambrosini, Carlos Castaneda, Jeffrey Finklestein, Xue-Lan Hu, Uma Mudunuri, Sheila Paul, and Jun Wei
Mapping and Initial Analysis of Human Subtelomeric Sequence Assemblies
Genome Res. 2004 14: 18-28. [Abstract] [Full Text] [Supplemental Research Data]  

Yuri I. Wolf, Igor B. Rogozin, and Eugene V. Koonin
Coelomata and Not Ecdysozoa: Evidence From Genome-Wide Phylogenetic Analysis
Genome Res. 2004 14: 29-36. [Abstract] [Full Text]  

Soojin Yi, Tyrone J. Summers, Nathaniel M. Pearson, and Wen-Hsiung Li
Recombination Has Little Effect on the Rate of Sequence Divergence in Pseudoautosomal Boundary 1 Among Humans and Great Apes
Genome Res. 2004 14: 37-43. Published in Advance December 12, 2003, 10.1101/gr.1777204 [Abstract] [Full Text] [Supplemental Research Data]  

Claude Rispe, François Delmotte, Roeland C.H.J. van Ham, and Andres Moya
Mutational and Selective Pressures on Codon and Amino Acid Usage in Buchnera, Endosymbiotic Bacteria of Aphids
Genome Res. 2004 14: 44-53. Published in Advance December 12, 2003, 10.1101/gr.1358104 [Abstract] [Full Text]  

Eitan E. Winter, Leo Goodstadt, and Chris P. Ponting
Elevated Rates of Protein Secretion, Evolution, and Disease Among Tissue-Specific Genes
Genome Res. 2004 14: 54-61. [Abstract] [Full Text] [Supplemental Research Data]  

Nathan D. Trinklein, Shelley Force Aldred, Sara J. Hartman, Diane I. Schroeder, Robert P. Otillar, and Richard M. Myers
An Abundance of Bidirectional Promoters in the Human Genome
Genome Res. 2004 14: 62-66. [Abstract] [Full Text] [Supplemental Research Data]  

Michael Weir and Michael Rice
Ordered Partitioning Reveals Extended Splice-Site Consensus Information
Genome Res. 2004 14: 67-78. [Abstract] [Full Text] [Supplemental Research Data]  

Theresa Zhang, Peter Haws, and Qiang Wu
Multiple Variable First Exons: A Mechanism for Cell- and Tissue-Specific Gene Regulation
Genome Res. 2004 14: 79-89. Published in Advance December 12, 2003, 10.1101/gr.1225204 [Abstract] [Full Text] [Supplemental Research Data]  

Hans Peter Fischer, Nina A. Brunner, Bernd Wieland, Jesse Paquette, Ludwig Macko, Karl Ziegelbauer, and Christoph Freiberg
Identification of Antibiotic Stress-Inducible Promoters: A Systematic Approach to Novel Pathway-Specific Reporter Assays for Antibacterial Drug Discovery
Genome Res. 2004 14: 90-98. [Abstract] [Full Text] [Supplemental Research Data]  

Moshe Pritsker, Yir-Chung Liu, Michael A. Beer, and Saeed Tavazoie
Whole-Genome Discovery of Transcription Factor Binding Sites by Network-Level Conservation
Genome Res. 2004 14: 99-108. Published in Advance December 12, 2003, 10.1101/gr.1739204 [Abstract] [Full Text] [HTML Page - index.htslp]  

METHODS:

Kam Jim, Kush Parmar, Mona Singh, and Saeed Tavazoie
A Cross-Genomic Approach for Systematic Mapping of Phenotypic Traits to Genes
Genome Res. 2004 14: 109-115. [Abstract] [Full Text] [Supplemental Research Data]  

Michael C. Rice, Brandy M. Heckman, Yi Liu, and Eric B. Kmiec
Fluorescent Detection and Isolation of DNA Variants Using Stabilized RecA-Coated Oligonucleotides
Genome Res. 2004 14: 116-125. Published in Advance December 12, 2003, 10.1101/gr.1386204 [Abstract] [Full Text]  

Patrick Stanssens, Marc Zabeau, Geert Meersseman, Gwen Remes, Yannick Gansemans, Niels Storm, Ralf Hartmer, Christiane Honisch, Charles P. Rodi, Sebastian Böcker, and Dirk van den Boom
High-Throughput MALDI-TOF Discovery of Genomic Sequence Polymorphisms
Genome Res. 2004 14: 126-133. [Abstract] [Full Text]  

Kevin J. Smylie, Charles R. Cantor, and Mikhail F. Denissenko
Analysis of Sequence Variations in Several Human Genes Using Phosphoramidite Bond DNA Fragmentation and Chip-Based MALDI-TOF
Genome Res. 2004 14: 134-141. [Abstract] [Full Text] [Supplemental Research Data]  

Jonathan E. Allen, Mihaela Pertea, and Steven L. Salzberg
Computational Gene Prediction Using Multiple Sources of Evidence
Genome Res. 2004 14: 142-148. [Abstract] [Full Text]  

Mihai Pop, Daniel S. Kosack, and Steven L. Salzberg
Hierarchical Scaffolding With Bambus
Genome Res. 2004 14: 149-159. [Abstract] [Full Text]  

RESOURCES:

Arek Kasprzyk, Damian Keefe, Damian Smedley, Darin London, William Spooner, Craig Melsopp, Martin Hammond, Philippe Rocca-Serra, Tony Cox, and Ewan Birney
EnsMart: A Generic System for Fast and Flexible Access to Biological Data
Genome Res. 2004 14: 160-169. [Abstract] [Full Text]  

Eugene Berezikov, Victor Guryev, Ronald H.A. Plasterk, and Edwin Cuppen
CONREAL: Conserved Regulatory Elements Anchored Alignment Algorithm for Identification of Transcription Factor Binding Sites by Phylogenetic Footprinting
Genome Res. 2004 14: 170-178. Published in Advance December 12, 2003, 10.1101/gr.1642804 [Abstract] [Full Text] [Supplemental Research Data]  

Joel Greshock, Tara L. Naylor, Adam Margolin, Sharon Diskin, Stephen H. Cleaver, P. Andrew Futreal, Pieter J. deJong, Shaying Zhao, Michael Liebman, and Barbara L. Weber
1-Mb Resolution Array-Based Comparative Genomic Hybridization Using a BAC Clone Set Optimized for Cancer Gene Analysis
Genome Res. 2004 14: 179-187. Published in Advance December 12, 2003, 10.1101/gr.1847304 [Abstract] [Full Text] [Supplemental Research Data]  

Yeun-Jun Chung, Jos Jonkers, Hannah Kitson, Heike Fiegler, Sean Humphray, Carol Scott, Sarah Hunt, Yuejin Yu, Ichiko Nishijima, Arno Velds, Henne Holstege, Nigel Carter, and Allan Bradley
A Whole-Genome Mouse BAC Microarray With 1-Mb Resolution for Analysis of DNA Copy Number Changes by Array Comparative Genomic Hybridization
Genome Res. 2004 14: 188-196. [Abstract] [Full Text] [Supplemental Research Data]  

ERRATA:

Correction for Volume 13, p. 2485
Genome Res. 2004 14: 197. [Full Text]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


Cover Caption:

Cover Cover The pufferfish genome has evolved to be among the smallest of all vertebrates, and its morphological features are also greatly simplified. As this alcian-stained 22 day larva of the pufferfish Takifugu rubripes shows, skeletal reductions include the loss of ribs,the loss of the pelvic girdle and pelvic fins, and greatly modified cranial skeleton. What is the relationship of genome reduction and the developmental mechanisms leading to morphological simplification? A paper in this month's issue explores this question by investigating the structure and developmental roles of Hox cluster genes in pufferfish embryos. (For details, see Amores et al., pp. 1-10. Photograph by Tohru Suzuki.)


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