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Volume 11, Issue 8: August 2001 [Index by Author]  [Cover Caption] 

Cover Image
Other Issues:
  INSIGHT/OUTLOOK
  ARTICLES
  LETTERS
  METHODS
  RESOURCES
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INSIGHT/OUTLOOK:

Andrew G. Clark
The Search for Meaning in Noncoding DNA
Genome Res. 2001 11: 1319-1320. [Full Text]  

Margaret G. Kidwell and Andrew J. Holyoake
Transposon-Induced Hotspots for Genomic Instability
Genome Res. 2001 11: 1321-1322. [Full Text]  

Thomas E. Johnson
SAGE Thoughts on Aging
Genome Res. 2001 11: 1323-1324. [Full Text]  

ARTICLES:

Mireille H. Lahoud, Sika Ristevski, Deon J. Venter, Lars S. Jermiin, Ivan Bertoncello, Silva Zavarsek, Sue Hasthorpe, John Drago, David de Kretser, Paul J. Hertzog, and Ismail Kola
Gene Targeting of Desrt, a Novel ARID Class DNA-Binding Protein, Causes Growth Retardation and Abnormal Development of Reproductive Organs
Genome Res. 2001 11: 1327-1334. Published in Advance July 12, 2001, 10.1101/gr.168801 [Abstract] [Full Text]  

Casey M. Bergman and Martin Kreitman
Analysis of Conserved Noncoding DNA in Drosophila Reveals Similar Constraints in Intergenic and Intronic Sequences
Genome Res. 2001 11: 1335-1345. [Abstract] [Full Text] [Supplemental Research Data]  

Steven J.M. Jones, Donald L. Riddle, Anatoli T. Pouzyrev, Victor E. Velculescu, LaDeana Hillier, Sean R. Eddy, Shawn L. Stricklin, David L. Baillie, Robert Waterston, and Marco A. Marra
Changes in Gene Expression Associated with Developmental Arrest and Longevity in Caenorhabditis elegans
Genome Res. 2001 11: 1346-1352. Published in Advance July 12, 2001, 10.1101/gr.184401 [Abstract] [Full Text]  

LETTERS:

Mario Cáceres, Marta Puig, and Alfredo Ruiz
Molecular Characterization of Two Natural Hotspots in the Drosophila buzzatii Genome Induced by Transposon Insertions
Genome Res. 2001 11: 1353-1364. Published in Advance July 12, 2001, 10.1101/gr.174001 [Abstract] [Full Text] [Supplemental Research Data]  

L. Aravind and Eugene V. Koonin
Prokaryotic Homologs of the Eukaryotic DNA-End-Binding Protein Ku, Novel Domains in the Ku Protein and Prediction of a Prokaryotic Double-Strand Break Repair System
Genome Res. 2001 11: 1365-1374. [Abstract] [Full Text]  

Laila Alves Nahum and Monica Riley
Divergence of Function in Sequence-Related Groups of Escherichia coli Proteins
Genome Res. 2001 11: 1375-1381. [Abstract] [Full Text]  

Debra J. Mathews, Carl Kashuk, Gale Brightwell, Evan E. Eichler, and Aravinda Chakravarti
Sequence Variation Within the Fragile X Locus
Genome Res. 2001 11: 1382-1391. [Abstract] [Full Text] [Supplemental Research Data]  

Yongtao Yu, Chenggang Zhang, Gangqiao Zhou, Songfeng Wu, Xianghu Qu, Handong Wei, Guichun Xing, Chunna Dong, Yun Zhai, Jinghong Wan, Shuguang Ouyang, Li Li, Shaowen Zhang, Kaixin Zhou, Yinan Zhang, Chutse Wu, and Fuchu He
Gene Expression Profiling in Human Fetal Liver and Identification of Tissue- and Developmental-Stage-Specific Genes through Compiled Expression Profiles and Efficient Cloning of Full-Length cDNAs
Genome Res. 2001 11: 1392-1403. [Abstract] [Full Text]  

METHODS:

Rickard Sandberg, Gösta Winberg, Carl-Ivar Bränden, Alexander Kaske, Ingemar Ernberg, and Joakim Cöster
Capturing Whole-Genome Characteristics in Short Sequences Using a Naïve Bayesian Classifier
Genome Res. 2001 11: 1404-1409. [Abstract] [Full Text]  

János Murvai, Kristian Vlahovicek, Csaba Szepesvári, and Sándor Pongor
Prediction of Protein Functional Domains from Sequences Using Artificial Neural Networks
Genome Res. 2001 11: 1410-1417. [Abstract] [Full Text]  

Shoulian Dong, Eugene Wang, Linda Hsie, Yanxiang Cao, Xiaogiong Chen, and Thomas R. Gingeras
Flexible Use of High-Density Oligonucleotide Arrays for Single-Nucleotide Polymorphism Discovery and Validation
Genome Res. 2001 11: 1418-1424. Published in Advance July 12, 2001, 10.1101/gr.171101 [Abstract] [Full Text]  

RESOURCES:

The Gene Ontology Consortium
Creating the Gene Ontology Resource: Design and Implementation
Genome Res. 2001 11: 1425-1433. [Abstract] [Full Text]  

Jeffrey P. Tomkins, Todd C. Wood, Minviluz G. Stacey, John T. Loh, Adam Judd, Jose L. Goicoechea, Gary Stacey, Michael J. Sadowsky, and Rod A. Wing
A Marker-Dense Physical Map of the Bradyrhizobium japonicum Genome
Genome Res. 2001 11: 1434-1440. [Abstract] [Full Text]  

Svetlana Temnykh, Genevieve DeClerck, Angelika Lukashova, Leonard Lipovich, Samuel Cartinhour, and Susan McCouch
Computational and Experimental Analysis of Microsatellites in Rice (Oryza sativa L.): Frequency, Length Variation, Transposon Associations, and Genetic Marker Potential
Genome Res. 2001 11: 1441-1452. [Abstract] [Full Text]  

Jean-Marie Rouillard, Ayse E. Erson, Rork Kuick, Jun-ichi Asakawa, Katharina Wimmer, Martine Muleris, Elizabeth M. Petty, and Samir Hanash
Virtual Genome Scan: A Tool for Restriction Landmark-Based Scanning of the Human Genome
Genome Res. 2001 11: 1453-1459. Published in Advance July 12, 2001, 10.1101/gr.181601 [Abstract] [Full Text]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


Cover Caption:

Cover

Separating genomic sequences from 28 eubacterial and archaes using principal component analysis (PCA). Twenty-five genomic sequences of 1000 base pairs were taken randomly from each of the 28 genomes, and the frequency of all short oligonucleotides with a length of six bases was recorded. The motif frequencies were then visualized in PCA space, drawn by principal component 4, 5, and 6. Genomic sequences taken from the same genome cluster in PCA space. (For details, see Sandberg et al., pp. 1404-1409.)



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