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Published online before print December 6, 2006
Genome Research, DOI: 10.1101/gr.5776007
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Review

Synthetic biology projects in vitro

Anthony C. Forster1,3 and George M. Church2,3

1 Department of Pharmacology and Vanderbilt Institute of Chemical Biology, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA; 2 Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA

Advances in the in vitro synthesis and evolution of DNA, RNA, and polypeptides are accelerating the construction of biopolymers, pathways, and organisms with novel functions. Known functions are being integrated and debugged with the aim of synthesizing life-like systems. The goals are knowledge, tools, smart materials, and therapies.

3 Corresponding authors.

E-mail a.forster{at}vanderbilt.edu; fax (615) 936-5555.

E-mail: http://arep.med.harvard.edu/; fax (617) 432-6513.

Article published online before print. Article and publication date are at http://www.genome.org/cgi/doi/10.1101/gr.5776007


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