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A contiguous high-resolution radiation hybrid map of 44 loci from the distal portion of the long arm of human chromosome 5.

Department of Biological Chemistry, College of Medicine, University of California, Irvine 92717, USA. janet_warrington@affymetrix.com

Abstract

A contiguous high-resolution map of 44 loci from a 35-Mb portion of the distal region of the long arm of human chromosome 5, q21-q35, was produced using radiation hybrid (RH) mapping in conjunction with a natural deletion mapping panel. The map includes 30 genes, four sequence-tagged site (STS) loci, and 10 DNA markers. Newly mapped markers fill two gap regions that were present in previous maps, between markers FER-IL4 and IL3-IL9. Identifying the position of genes on the physical map aids in positional cloning efforts and contributes to our understanding of the overall organization of the human genome.

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