Genome Research scroll

Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
QUICK SEARCH:   [advanced]


     

Published online before print November 7, 2007, 10.1101/gr.7156307
Genome Res. 17:1783-1786, 2007
©2007 by Cold Spring Harbor Laboratory Press; ISSN 1088-9051/07 $5.00
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
gr.7156307v1
17/12/1783    most recent
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Matise, T. C.
Right arrow Articles by Buyske, S.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Matise, T. C.
Right arrow Articles by Buyske, S.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?

Resource

A second-generation combined linkage–physical map of the human genome

Tara C. Matise1,10, Fang Chen1, Wenwei Chen2, Francisco M. De La Vega3, Mark Hansen4, Chunsheng He1,7, Fiona C.L. Hyland3, Giulia C. Kennedy2, Xiangyang Kong1,8, Sarah S. Murray4,9, Janet S. Ziegle3, William C.L. Stewart5, and Steven Buyske1,6

1 Department of Genetics, Rutgers University, Piscataway, New Jersey 08854, USA; 2 Affymetrix, Inc., Santa Clara, California 95051, USA; 3 Applied Biosystems, Inc., Foster City, California 94404, USA; 4 Illumina, Inc., San Diego, California 92121, USA; 5 Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48104, USA; 6 Department of Statistics and Biostatistics, Rutgers University, Piscataway, New Jersey 08854, USA

We have completed a second-generation linkage map that incorporates sequence-based positional information. This new map, the Rutgers Map v.2, includes 28,121 polymorphic markers with physical positions corroborated by recombination-based data. Sex-averaged and sex-specific linkage map distances, along with confidence intervals, have been estimated for all map intervals. In addition, a regression-based smoothed map is provided that facilitates interpolation of positions of unmapped markers on this map. With nearly twice as many markers as our first-generation map, the Rutgers Map continues to be a unique and comprehensive resource for obtaining genetic map information for large sets of polymorphic markers.

7 Present addresses: Laboratory of Statistical Genetics, Rockefeller University, New York, NY 10065, USA;

8 Glaxo Smithkline, Research Triangle Park, NC 27709, USA;

9 Scripps Genomic Medicine, La Jolla, CA 92037, USA.

10 Corresponding author.

E-mail matise{at}biology.rutgers.edu; fax (732) 445-4972.

Article published online before print. Article and publication date are at http://www.genome.org/cgi/doi/10.1101/gr.7156307


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?




Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
Genes Dev. Learn. Mem.
Protein Science RNA Genome Res.
Copyright © 2007 by Cold Spring Harbor Laboratory Press.