This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Little, P. F.R. Search for Related Content PubMed PubMed Citation Articles by Little, P. F.R. Social Bookmarking                   What's this?

Perspective

Structure and function of the human genome

School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney 2074, New South Wales, Australia

The human genome project has had an impact on both biological research and its political organization; this review focuses primarily on the scientific novelty that has emerged from the project but also touches on its political dimensions. The project has generated both anticipated and novel information; in the later category are the description of the unusual distribution of genes, the prevalence of non-protein-coding genes, and the extraordinary evolutionary conservation of some regions of the genome. The applications of the sequence data are just starting to be felt in basic, rather than therapeutic, biomedical research and in the vibrant human origins and variation debates. The political impact of the project is in the unprecedented extent to which directed funding programs have emerged as drivers of basic research and the organization of the multidisciplinary groups that are needed to utilize the human DNA sequence.

Article and publication are at http://www.genome.org/cgi/doi/10.1101/gr.4560905.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?

This article has been cited by other articles:

				C. Zhang MicroRNomics: a newly emerging approach for disease biology Physiol Genomics, April 21, 2008; 33(2): 139 - 147. [Abstract] [Full Text] [PDF]