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Published online before print September 16, 2005, 10.1101/gr.3672305
Genome Res. 15:1456-1461, 2005
©2005 by Cold Spring Harbor Laboratory Press; ISSN 1088-9051/05 $5.00
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The Yeast Gene Order Browser: Combining curated homology and syntenic context reveals gene fate in polyploid species

Kevin P. Byrne and Kenneth H. Wolfe1

Department of Genetics, Smurfit Institute, University of Dublin, Trinity College, Dublin 2, Ireland

We developed the Yeast Gene Order Browser (YGOB; http://wolfe.gen.tcd.ie/ygob) to facilitate visual comparisons and computational analysis of synteny relationships in yeasts. The data presented in YGOB, currently covering seven species, are based on sets of homologous genes that have been intensively manually curated based on both sequence similarity and genomic context (synteny). We reconciled different laboratories' lists of paralogous Saccharomyces cerevisiae gene pairs formed by genome duplication (ohnologs), and present near-exhaustive lists of the ohnolog pairs retained in S. cerevisiae (551, including 22 previously unidentified), Saccharomyces castellii (599), and Candida glabrata (404).

Article and publication are at http://www.genome.org/cgi/doi/10.1101/gr.3672305. Article published online before print in September 2005.

1 Corresponding author.
E-mail khwolfe{at}tcd.ie; fax 353-1-679-8558.

[Supplemental material is available online at www.genome.org.]


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