Genome Research scroll

Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
QUICK SEARCH:   [advanced]


     

Published online before print December 30, 2002, 10.1101/gr.858103
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Supplemental Research Data
Right arrow All Versions of this Article:
GR-8581Rv1
13/1/122    most recent
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Rowe, L. B.
Right arrow Articles by Eppig, J. T.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Rowe, L. B.
Right arrow Articles by Eppig, J. T.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?
Vol 13, Issue 1, 122-133, January 2003

RESOURCES

The Comprehensive Mouse Radiation Hybrid Map Densely Cross-Referenced to the Recombination Map: A Tool to Support the Sequence Assemblies

Lucy B. Rowe1, Mary E. Barter, Jennifer A. Kelmenson and Janan T. Eppig

The Jackson Laboratory, Bar Harbor, Maine 04609, USA

We have developed a unique comprehensive mouse radiation hybrid (RH) map of nearly 23,000 markers integrating data from three international genome centers and over 400 independent laboratories. We have cross-referenced this map to the 0.5-cM resolution recombination-based Jackson Laboratory (TJL) backcross panel map, building a complete set of RH framework chromosome maps based on a high density of known-ordered anchor markers. We have systematically typed markers to improve coverage and resolve discrepancies, and have reanalyzed data sets as needed. The cross-linking of the RH and recombination maps has resulted in a highly accurate genome-wide map with consistent marker order. We have compared these linked framework maps to the Ensembl mouse genome sequence assembly, and show that they are a useful medium resolution tool for both validating sequence assembly and elucidating chromosome biology.

[Supplemental material is available online at www.genome.org.]

1 Corresponding author.

E-MAIL lbr{at}jax.org; FAX (207) 288-6072.

Article and publication are at http://www.genome.org/cgi/doi/10.1101/gr.858103. Article published online before print in December 2002.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?


This article has been cited by other articles:


Home page
 Genome Res.Home page
L. Wilson, Y.-H. Ching, M. Farias, S. A. Hartford, G. Howell, H. Shao, M. Bucan, and J. C. Schimenti
Random mutagenesis of proximal mouse chromosome 5 uncovers predominantly embryonic lethal mutations
Genome Res., August 1, 2005; 15(8): 1095 - 1105.
[Abstract] [Full Text] [PDF]

Home page
 Genome Res.Home page
J. Zhang, K. W. Hunter, M. Gandolph, W. L. Rowe, R. P. Finney, J. M. Kelley, M. Edmonson, and K. H. Buetow
A high-resolution multistrain haplotype analysis of laboratory mouse genome reveals three distinctive genetic variation patterns
Genome Res., February 1, 2005; 15(2): 241 - 249.
[Abstract] [Full Text] [PDF]

Home page
 Genome Res.Home page
P. M. Petkov, Y. Ding, M. A. Cassell, W. Zhang, G. Wagner, E. E. Sargent, S. Asquith, V. Crew, K. A. Johnson, P. Robinson, et al.
An Efficient SNP System for Mouse Genome Scanning and Elucidating Strain Relationships
Genome Res., September 1, 2004; 14(9): 1806 - 1811.
[Abstract] [Full Text] [PDF]


Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
Genes Dev. Learn. Mem.
Protein Science RNA Genome Res.