Genome Research

Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
QUICK SEARCH:   [advanced]


     

Published online before print November 12, 2001, 10.1101/gr.200801
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
GR-2008Rv1
11/12/2101    most recent
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Boudet, N.
Right arrow Articles by Lecharny, A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Boudet, N.
Right arrow Articles by Lecharny, A.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?

Vol. 11, Issue 12, 2101-2114, December 2001

LETTER
Evolution of Intron/Exon Structure of DEAD Helicase Family Genes in Arabidopsis, Caenorhabditis, and Drosophila

Nathalie Boudet,1 Sébastien Aubourg,1,2 Claire Toffano-Nioche,1 Martin Kreis,1 and Alain Lecharny1,3

1 Institut de Biotechnologie des Plantes, Unité Mixte de Recherche-Centre National Recherche Scientifique 8618, Université de Paris-Sud, Bât. 630, F-91405 Orsay Cedex, France

The DEAD box RNA helicase (RH) proteins are homologs involved in diverse cellular functions in all of the organisms from prokaryotes to eukaryotes. Nevertheless, there is a lack of conservation in the splicing pattern in the 53 Arabidopsis thaliana (AtRHs), the 32 Caenorhabditis elegans (CeRHs) and the 29 Drosophila melanogaster (DmRHs) genes. Of the 153 different observed intron positions, 4 are conserved between AtRHs, CeRHs, and DmRHs, and one position is also found in RHs from yeast and human. Of the 27 different AtRH structures with introns, 20 have at least one predicted ancient intron in the regions coding for the catalytic domain. In all of the organisms examined, we found at least one gene with most of its intron predicted to be ancient. In A. thaliana, the large diversity in RH structures suggests that duplications of the ancestral RH were followed by a high number of intron deletions and additions. The very high bias toward phase 0 introns is in favor of intron addition, preferentially in phase 0. Results from this comparative study of the same gene family in a plant and in two animals are discussed in terms of the general mechanisms of gene family evolution.

2 Present address: Unité de Recherche en Génomique Végétale, INRA, FRE-CNRS, 2 rue Gaston Crémieux, CP 5708, F-91057 Evry Cedex, France.

3 Corresponding author.

11:2101-2114 ©2001 by Cold Spring Harbor Laboratory Press  ISSN 1088-9051/01 $5.00
Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?


This article has been cited by other articles:


Home page
 Plant Physiol.Home page
A. Matthes, S. Schmidt-Gattung, D. Kohler, J. Forner, S. Wildum, M. Raabe, H. Urlaub, and S. Binder
Two DEAD-Box Proteins May Be Part of RNA-Dependent High-Molecular-Mass Protein Complexes in Arabidopsis Mitochondria
Plant Physiology, December 1, 2007; 145(4): 1637 - 1646.
[Abstract] [Full Text] [PDF]

Home page
 Plant Physiol.Home page
P. Kant, S. Kant, M. Gordon, R. Shaked, and S. Barak
STRESS RESPONSE SUPPRESSOR1 and STRESS RESPONSE SUPPRESSOR2, Two DEAD-Box RNA Helicases That Attenuate Arabidopsis Responses to Multiple Abiotic Stresses
Plant Physiology, November 1, 2007; 145(3): 814 - 830.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
S. R. Schulze, B. F. McAllister, D. A. R. Sinclair, K. A. Fitzpatrick, M. Marchetti, S. Pimpinelli, and B. M. Honda
Heterochromatic Genes in Drosophila: A Comparative Analysis of Two Genes
Genetics, July 1, 2006; 173(3): 1433 - 1445.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
V. N. Babenko, I. B. Rogozin, S. L. Mekhedov, and E. V. Koonin
Prevalence of intron gain over intron loss in the evolution of paralogous gene families
Nucleic Acids Res., July 14, 2004; 32(12): 3724 - 3733.
[Abstract] [Full Text] [PDF]

Home page
 Genome Res.Home page
Z. Zhang, P. E. Burch, A. J. Cooney, R. B. Lanz, F. A. Pereira, J. Wu, R. A. Gibbs, G. Weinstock, and D. A. Wheeler
Genomic Analysis of the Nuclear Receptor Family: New Insights Into Structure, Regulation, and Evolution From the Rat Genome
Genome Res., April 1, 2004; 14(4): 580 - 590.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
R. Tarrio, F. Rodriguez-Trelles, and F. J. Ayala
A new Drosophila spliceosomal intron position is common in plants
PNAS, May 27, 2003; 100(11): 6580 - 6583.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
E. Bon, S. Casaregola, G. Blandin, B. Llorente, C. Neuveglise, M. Munsterkotter, U. Guldener, H.-W. Mewes, J. V. Helden, B. Dujon, et al.
Molecular evolution of eukaryotic genomes: hemiascomycetous yeast spliceosomal introns
Nucleic Acids Res., February 15, 2003; 31(4): 1121 - 1135.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
F. Hartung, F. R. Blattner, and H. Puchta
Intron gain and loss in the evolution of the conserved eukaryotic recombination machinery
Nucleic Acids Res., December 1, 2002; 30(23): 5175 - 5181.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
Z. Gong, H. Lee, L. Xiong, A. Jagendorf, B. Stevenson, and J.-K. Zhu
RNA helicase-like protein as an early regulator of transcription factors for plant chilling and freezing tolerance
PNAS, August 20, 2002; 99(17): 11507 - 11512.
[Abstract] [Full Text] [PDF]


Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
Genes Dev. Learn. Mem.
Protein Science RNA Genome Res.